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Temperature modulation is expected to receive FDA clearance in the second quarter, and to initially have the same clearance as the Celsius Control System. Tight supplies cause crude futures to jump. Neuroscientists Find That Men And Women Respond Differently To Stress. You folks have no clue about Canadian health care. Cuba showed how they took better care of the rescuers than Rudy did. Constitution Sorry for the rant but I haven't slept in days trying to bolster my facts.
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The companys President and Chief Executive Officer, Neil Kurtz, M.D., will moderate a discussion following brief presentations by:
Tony Yaksh, Ph.D., Professor and Vice Chairman for Research, Department of Anesthesiology, and Professor of Pharmacology at the University of California, San Diego
Dr. Yaksh will present information about glutamate receptors in the central nervous system as a target for chronic pain therapy. The focus of his research is the physiology and pharmacology of pain processing. A member of numerous professional societies, Dr. Yaksh has been a consultant to the U.S. Food and Drug Administration and serves on the editorial boards of several journals. He has received many awards, including the FWL Kerr Award from the American Pain Society and the American Society of Anesthesiology Award for Excellence in Research.
Jerome Goldstein, M.D., Director of the San Francisco Headache Clinic and a board-certified neurologist who focuses on the diagnosis, treatment, prevention and cure of headache
Dr. Goldstein will present information about glutamate receptors in the brain as a target for acute and prophylactic migraine therapy. He is a member of the American Headache Society, The International Headache Society and The National Headache Foundation. Dr. Goldstein is a Board Certified Neurologist, a Fellow of the American Academy of Neurology, and has special qualification for the treatment of headache from the National Headache Foundation. He has received many industry awards, published articles in industry journals and served on advisory boards related to the development of a wide range of headache therapies.
Alan J. Tuchman, M.D., Clinical Professor of Neurology and Pharmacology at New York Medical College, Principal of a neuroscience-focused consulting firm and a board-certified neurologist
Dr. Tuchman will present information about glutamate receptors in the spinal cord as a target for muscle spasticity. He has served as Vice Chairman of the Department of Neurology at New York Medical College as well as Vice Dean of Clinical Affairs, which involved the development and management of clinical care and medical education policy for 29 affiliated hospitals. In addition, he was President of the Epilepsy Society of Southern New York. Dr. Tuchman is a frequent speaker about neuroscience topics at academic meetings.
s a growing body of scientific and clinical evidence that supports the further development of drugs that block the glutamate cascade, said Dr. Kurtz. As the American Headache Society prepares to kick off its 50th Annual Scientific Meeting, we want to provide patients as well as the medical community with industry experts perspectives as to what is clearly a promising approach for the treatment of migraine and other conditions.
TorreyPines Therapeutics lead compound, tezampanel is the first AMPA/kainate-type glutamate receptor antagonist to be studied in clinical trials for chronic pain. Glutamate receptors mediate the functioning of glutamate, an important excitatory neurotransmitter. While normal glutamate production is essential, excess glutamate production, either through injury or disease, can have a range of pathological effects. By acting at both the AMPA and kainate receptor site to competitively block the binding of glutamate, tezampanel and its oral prodrug, NGX426, have the potential to treat a number of diseases and disorders. These include migraine and other forms of chronic pain such as neuropathic pain as well as muscle spasticity and rigidity secondary to spinal cord trauma, stroke and multiple sclerosis.
Webinar Information
Participants can access the Webinar by clicking on the link located on the home page of TorreyPines Therapeutics Web site at http://www.torreypinestherapeutics.com. Individuals interested in asking questions should also participate via telephone by calling 888-823-7457 in the United States or 973-935-8504 outside of the United States and entering conference ID 48658866. Participants are encouraged to log on at least 15 minutes prior to the beginning of the Webinar. A replay of the Webinar will be available on TorreyPines Therapeutics Web site until July 25.
About TorreyPines Therapeutics
TorreyPines Therapeutics, Inc. is a biopharmaceutical company committed to providing patients with better alternatives to existing therapies through the research, development and commercialization of small molecule compounds. The companys goal is to develop versatile product candidates, each capable of treating a number of acute and chronic diseases and disorders such as migraine, chronic pain, muscle spasticity and rigidity, xerostomia and cognitive disorders. The company is currently developing four product candidates: two ionotropic glutamate receptor antagonists and two muscarinic receptor agonists. Further information is available at http://www.torreypinestherapeutics.com.
This press release contains forward-looking statements or predictions. Such forward-looking statements include, but are not limited to, statements regarding the potential for tezampanel and NGX426 as treatments for migraine and other forms of chronic pain such as neuropathic pain as well as muscle spasticity and rigidity secondary to spinal cord trauma, stroke and multiple sclerosis. Such statements are subject to numerous known and unknown risks, uncertainties and other factors, which may cause TorreyPines actual results to be materially different from historical results or from any results expressed or implied by such forward-looking statements, including whether any preclinical studies or clinical trials conducted in the future, will prove successful, and if successful, whether the results can be replicated. These and other risks which may cause results to differ are described in greater detail in the Risk Factors section of TorreyPines annual report on Form 10- K for the year ended December 31, 2007 and TorreyPines other SEC reports. The forward-looking statements are based on current information that is likely to change and speak only as of the date hereof.
Company Contact: Media Contact:
Paul Schneider David Schull
TorreyPines Therapeutics, Inc. Russo Partners, LLC
858-623-5665, x125 212-845-4271
pschneider@torreypinestherapeutics.com david.schull@russopartnersllc.com
Investor Contact:
Rhonda Chiger
Rx Communications
917-322-2569
rchiger@rxir.com
SOURCE TorreyPines Therapeutics, Inc.
http://www.torreypinestherapeutics.com
Copyright (C) 2008 PR Newswire.
Read more...
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The companys President and Chief Executive Officer, Neil Kurtz, M.D., will moderate a discussion following brief presentations by:
Tony Yaksh, Ph.D., Professor and Vice Chairman for Research, Department of Anesthesiology, and Professor of Pharmacology at the University of California, San Diego
Dr. Yaksh will present information about glutamate receptors in the central nervous system as a target for chronic pain therapy. The focus of his research is the physiology and pharmacology of pain processing. A member of numerous professional societies, Dr. Yaksh has been a consultant to the U.S. Food and Drug Administration and serves on the editorial boards of several journals. He has received many awards, including the FWL Kerr Award from the American Pain Society and the American Society of Anesthesiology Award for Excellence in Research.
Jerome Goldstein, M.D., Director of the San Francisco Headache Clinic and a board-certified neurologist who focuses on the diagnosis, treatment, prevention and cure of headache
Dr. Goldstein will present information about glutamate receptors in the brain as a target for acute and prophylactic migraine therapy. He is a member of the American Headache Society, The International Headache Society and The National Headache Foundation. Dr. Goldstein is a Board Certified Neurologist, a Fellow of the American Academy of Neurology, and has special qualification for the treatment of headache from the National Headache Foundation. He has received many industry awards, published articles in industry journals and served on advisory boards related to the development of a wide range of headache therapies.
Alan J. Tuchman, M.D., Clinical Professor of Neurology and Pharmacology at New York Medical College, Principal of a neuroscience-focused consulting firm and a board-certified neurologist
Dr. Tuchman will present information about glutamate receptors in the spinal cord as a target for muscle spasticity. He has served as Vice Chairman of the Department of Neurology at New York Medical College as well as Vice Dean of Clinical Affairs, which involved the development and management of clinical care and medical education policy for 29 affiliated hospitals. In addition, he was President of the Epilepsy Society of Southern New York. Dr. Tuchman is a frequent speaker about neuroscience topics at academic meetings.
s a growing body of scientific and clinical evidence that supports the further development of drugs that block the glutamate cascade, said Dr. Kurtz. As the American Headache Society prepares to kick off its 50th Annual Scientific Meeting, we want to provide patients as well as the medical community with industry experts perspectives as to what is clearly a promising approach for the treatment of migraine and other conditions.
TorreyPines Therapeutics lead compound, tezampanel is the first AMPA/kainate-type glutamate receptor antagonist to be studied in clinical trials for chronic pain. Glutamate receptors mediate the functioning of glutamate, an important excitatory neurotransmitter. While normal glutamate production is essential, excess glutamate production, either through injury or disease, can have a range of pathological effects. By acting at both the AMPA and kainate receptor site to competitively block the binding of glutamate, tezampanel and its oral prodrug, NGX426, have the potential to treat a number of diseases and disorders. These include migraine and other forms of chronic pain such as neuropathic pain as well as muscle spasticity and rigidity secondary to spinal cord trauma, stroke and multiple sclerosis.
Webinar Information
Participants can access the Webinar by clicking on the link located on the home page of TorreyPines Therapeutics Web site at http://www.torreypinestherapeutics.com. Individuals interested in asking questions should also participate via telephone by calling 888-823-7457 in the United States or 973-935-8504 outside of the United States and entering conference ID 48658866. Participants are encouraged to log on at least 15 minutes prior to the beginning of the Webinar. A replay of the Webinar will be available on TorreyPines Therapeutics Web site until July 25.
About TorreyPines Therapeutics
TorreyPines Therapeutics, Inc. is a biopharmaceutical company committed to providing patients with better alternatives to existing therapies through the research, development and commercialization of small molecule compounds. The companys goal is to develop versatile product candidates, each capable of treating a number of acute and chronic diseases and disorders such as migraine, chronic pain, muscle spasticity and rigidity, xerostomia and cognitive disorders. The company is currently developing four product candidates: two ionotropic glutamate receptor antagonists and two muscarinic receptor agonists. Further information is available at http://www.torreypinestherapeutics.com.
This press release contains forward-looking statements or predictions. Such forward-looking statements include, but are not limited to, statements regarding the potential for tezampanel and NGX426 as treatments for migraine and other forms of chronic pain such as neuropathic pain as well as muscle spasticity and rigidity secondary to spinal cord trauma, stroke and multiple sclerosis. Such statements are subject to numerous known and unknown risks, uncertainties and other factors, which may cause TorreyPines actual results to be materially different from historical results or from any results expressed or implied by such forward-looking statements, including whether any preclinical studies or clinical trials conducted in the future, will prove successful, and if successful, whether the results can be replicated. These and other risks which may cause results to differ are described in greater detail in the Risk Factors section of TorreyPines annual report on Form 10- K for the year ended December 31, 2007 and TorreyPines other SEC reports. The forward-looking statements are based on current information that is likely to change and speak only as of the date hereof.
Company Contact: Media Contact:
Paul Schneider David Schull
TorreyPines Therapeutics, Inc. Russo Partners, LLC
858-623-5665, x125 212-845-4271
pschneider@torreypinestherapeutics.com david.schull@russopartnersllc.com
Investor Contact:
Rhonda Chiger
Rx Communications
917-322-2569
rchiger@rxir.com
SOURCE TorreyPines Therapeutics, Inc.
http://www.torreypinestherapeutics.com
Copyright (C) 2008 PR Newswire.
Read more...
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Please read the questions well, mark the answer sheets within 3 hours, and finally verify your answers and calculate your score. The pass mark is usually around 70%.
Don’t leave any question unmarked, as there is no penalty for wrong ones. Always start with the MCQs paper as it has the bulk of the score (250/300) and is easier to “navigate”. During the last quarter of hour, rapidly review your answers and check them carefully on the answer sheets.
I received many email suggesting the addition of online interactive questions with a computerized scoring system to our website. Personally, I discourage such “a process of practicing” the MRCP examination is neither computer based nor internet based; it is paper based. Many candidates simply fail because of unfamiliarity with the examination environment and wrong way of answering and marking the answer sheets. Try to imaging yourself in the examination hall, print this mock and solve it.
Eid Mabrook, Merry Xmas, and Happy New Year…
I wish you all the best and good luck…
Dr. Osama SM Amin MBChB MRCP(I) MRCPS(Glasg)
Head of Neurology4MRCP.
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Lippincott Williams Wilkina and the American Academy of Neurolohy Renew Publishing Partnership
Lippincott Williams Wilkins, part of Wolters Kluwer Health, has signed a five-year agreement to continue as the publisher for the American Academy of Neurology. The four-journal contract includes the prestigious professional research journal, Neurology, and Neurology Now, a magazine for patients and their families. LWW has been the publisher of Neurology since 1997 and launched AANs highly successful Neurology Now in 2005.
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Lippincott Williams Wilkins and the American Academy of Neurology Renew Publishing Partnership
Lippincott Williams Wilkins, part of Wolters Kluwer Health, has signed a five-year agreement to continue as the publisher for the American Academy of Neurology. The four-journal contract includes the prestigious professional research journal, Neurology, and Neurology Now, a magazine for patients and their families. LWW has been the publisher of Neurology since 1997 and launched AAN's highly successful Neurology Now in 2005.
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Lippincott Williams Wilkins and the American Academy of Neurology Renew Publishing Partnership
Lippincott Williams Wilkins, part of Wolters Kluwer Health, has signed a five-year agreement to continue as the publisher for the American Academy of Neurology. The four-journal contract includes the prestigious professional research journal, Neurology, and Neurology Now, a magazine for patients and their families. LWW has been the publisher of Neurology since 1997 and launched AAN's highly successful Neurology Now in 2005.
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, a magazine for patients and their families. LWW has been the publisher of Neurology since 1997 and launched AANs highly successful Neurology Now in 2005.
As the population ages and advancements in neurological disease treatment become ever more critical, we are pleased to work with a publisher who supports our mission of providing high quality research and information to both medical professionals and patients, said Bruce Polsky, Chief Executive Officer of AAN Enterprises, Inc., and responsible for all AAN Press publications.
We are honored that the AAN has chosen to continue our publishing relationship at such an important time of growth and discovery in the field of neurology, said Betsy Jones, EVP and GM of journal publishing at Wolters Kluwer Health. With new developments in disease areas like Alzheimers, Parkinsons, and multiple sclerosis on the horizon, our goal is to ensure that the highest quality professional, peer-reviewed research and information is made available through a trusted and premier medical society like the AAN.
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Additional Data Demonstrate Predictable, Extended Exposure with Sustained-
Release Formulation
CHICAGO, April 17 /PRNewswire/ -- Data from the first pivotal study of XP13512/GSK1838262, a sustained-release investigational compound to treat Restless Legs Syndrome (RLS), showed that it significantly improved the symptoms of moderate-to-severe primary RLS compared to placebo, and was generally well-tolerated when administered once-daily for 12 weeks.
Data from the PIVOT RLS I (Patient Improvement in Vital Outcomes following Treatment for RLS) clinical trial, formerly designated as study XP052, were presented today at the 60th annual meeting of the American Academy of Neurology (AAN).
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